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Dr. Pengfei Li (李鹏飞)
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Dr. Pengfei Li's Blog:
Address:
1 West Building, 99 Yanxiang Road, Xi’an,
Shaanxi, Province, 710054,
P. R. China
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Tel: 86-29-83395337
Fax: 86-29-83395132
Employment
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Jul/2015 –
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Professor (教授)
Organic Chemistry Research Center (OCRC)
Frontier Institute of Science and Technology (FIST),
Xi’an Jiaotong University (XJTU), Xi’an, China
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May/2014 –Jun/2015
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Lab Director II (实验室主任II类)
Organic Chemistry Research Center (OCRC)
Frontier Institute of Science and Technology (FIST),
Xi’an Jiaotong University (XJTU), Xi’an, China
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Nov/2011 – Apr/2014
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Principal Investigator at the level of Professor,
Group Leader I (研究小组主任I类)
Organic Chemistry Research Center (OCRC)
Frontier Institute of Science and Technology (FIST),
Xi’an Jiaotong University (XJTU), Xi’an, China
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Mar/2010 – Oct/2011
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Postdoctoral Associate (Advisor: Prof. Stephen L. Buchwald)
Department of Chemistry
Massachusetts Institute of Technology, Cambridge, MA, USA
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Apr/2005 – Sep/2006
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Research chemist, Basilea Pharmaceutica (China) Ltd, Haimen, China
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Jul/2004 – Mar/2005
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Research chemist, Chinese Wisdom Institute of Medicine and Wisdom Pharmaceutica Co. Ltd, Haimen, China
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Education
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Oct/2006 – Feb/2010
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Ph.D. in Organic Chemistry (Advisor: Prof. Dirk Menche)
Dissertation: Total synthesis of etnangien and studies towards the
total synthesis of rhizopodin
Heidelberg University, Heidelberg, and Helmholtz Center for Infection Research (HZI), Braunschweig, Germany
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Sep/2001 – Jun/2004
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M.S. in Organic Chemistry (Advisor: Prof. Zheng-Ming Li)
Dissertation: Synthesis and biological activities of novel
sulfonylurea compounds
Nankai University, Tianjin, China
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Sep/1997 – Jul/2001
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B.S. in Chemistry, Shanxi Normal University, Linfen, China
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Honors and Awards
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2015
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Thieme Chemistry Journal Award, Germany
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2015
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“陕西省青年科技新星”, Shaanxi Province
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2010
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The highest honor (summa cum laude) for the Ph.D. dissertation in
Heidelberg University, Germany
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Research Interests
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| Aromatic compounds as feedstocks, ligands (or catalysts) in catalytic C-X bond (X = B, Si, N, O) formation for making functional molecules.
Key words: catalysis, aromatic compounds, organoboron, C-X bond
1. Aromatic boron-centered ligands in catalysis.
2. Aromatic boron compounds: catalytic synthesis and transformations.
3. Catalytic dearomative reactions and their applications in synthesis of bioactive molecules.
4. High value-added fine chemicals by catalytic C-H to C-X transformations of arenes.
5. Catalytic synthesis of chiral polyaromatics as next generation OLED materials.
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Representative Publications
1. Guanghui Wang, Liang Xu and Pengfei Li,* Double N,B-type Bidentate Boryl Ligands Enabling a Highly Active Iridium Catalyst for C-H Borylation, J. Am. Chem. Soc. 2015, 137, 8058-8061.
2. Liang Xu, Shuai Zhang, Pengfei Li,* Boron-selective reactions as powerful tools for modular synthesis of diverse complex molecules, Chem. Soc. Rev. 2015, 44, DOI:10.1039/c5cs00338.
3. Liang Xu, Siyi Ding, Pengfei Li,* Site-differentiated Polyboron Arenes Prepared by Direct C-H Borylation and Their Highly Selective Suzuki-Miyaura Cross-Coupling Reactions, Angew. Chem. Int. Ed. 2014, 53, 1822-1826.
4. Guanghu Tong, Zhi Liu, Pengfei Li,* Stereocontrolled Construction of the Tricyclic Framework of Tiglianes and Daphnanes by an Oxidative Dearomatization Approach, Org. Lett. 2014, 16, 2288-2291.
5. Xiaowu Liu, Fei Xiong, Xuanping Huang, Liang Xu, Pengfei Li,* and Xiaoxing Wu,* Copper-Catalyzed Trifluoromethylation-Triggered Neophyl-Type Rearrangement of α,α-Diaryl Allylic Alcohols, Angew. Chem. Int. Ed. 2013, 52, 6962-6966.
6. Pengfei Li,* Jason S. Moore, Klavs F. Jensen,* A Microfluidic System for the Continuous Recycling of Unmodified Homogeneous Palladium Catalysts via Liquid-Liquid Phase Separation, ChemCatChem 2013, 5, 1729-1733.
7. Pengfei Li, Stephen L. Buchwald,* Continuous-Flow Synthesis of 3,3-Disubstituted Oxindoles by a Palladium-Catalyzed -Arylation/Alkylation Sequence, Angew. Chem. Int. Ed. 2011, 50, 6396-6400.
8. Pengfei Li, Jun Li, Fatih Arikan, Wiebke Ahlbrecht, Michael Dieckmann, Dirk Menche*, Stereoselective Total Synthesis of Etnangien and Etnangien Methyl Ester, J. Org. Chem. 2010, 75, 2429-2444.
9. Pengfei Li, Jun Li, Fatih Arikan, Wiebke Ahlbrecht, Michael Dieckmann, Dirk Menche*, Total Synthesi of Etnangien, J. Am. Chem. Soc. 2009, 131, 11678-11679.
10. Pengfei Li, Dirk Menche*, Cycloadditions in the Total Synthesis of Sporolide B, Angew. Chem. Int. Ed. 2009, 48, 5078-5080.
For a full list of publications, see Research ID: E-3211-2012.
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